Lexical Definition

‎אָכֵן‎ ʼâkên (aw-kane') surely H:Adv
from ‎כּוּן‎ (compare ‎כֵּן‎)

but, certainly, nevertheless, surely, truly, verily.

1) surely, truly, indeed
1a) truly, indeed (strong assertive force)
1b) but indeed, but in fact (emphasizing a contrast)

See Greek: ὄντως · οὗτος · οὗτος · πλήν

Usage: 9 forms in 18 verses
Form Translated As     In Verse(s)
אָכֵן֩ truly Jer.4.10
אָכֵן֙ nevertheless Isa.49.4Zeph.3.7
truly Gen.28.161Kgs.11.2Jer.3.23Jer.8.8
אָכֵ֥ן truly Isa.40.7Jer.3.23
אָכֵ֤ן nevertheless Isa.53.4
אָכֵ֛ן nevertheless Jer.3.20
אָכֵ֗ן nevertheless Ps.31.22
אָכֵ֖ן truly Exod.2.141Sam.15.32
אָכֵ֕ן truly Isa.45.15
אָ֭כֵן nevertheless Job.32.8Ps.66.19Ps.82.7

Brown-Driver-Briggs

‎אָכֵן‎ (perhaps from ‎אַח‎; compare Aramaic ‎דֵּח‎ & ‎דִּכֵּן‎) adverb with strong asseverative force:
a. surely, truly, especially at beginning of a speech (stronger & more decided than ‎אַח‎) Gen 28:16; Exod 2:14; 1Sam 15:32; Isa 40:7; Isa 45:15; Jer 3:23 (twice in verse); Jer 4:10; Jer 8:8. In 1Kgs 11:2 ‎אָבֵן‎ stands unusually; and ‎פֶּןֿ‎ (compare ᵐ5 ᵑ6 ᵑ7) should probably be read (so Klo).
b. emphasizing a contrast, but indeed, but in fact, especially after ‎אָמַרְתִּי‎ I said or thought, expressing the reality, in opposed to what had been wrongly imagined, Isa 49:4b (opposed to va) Isa 53:4 (opposed to vIsa 53:3 end) Jer 3:20 (opposed to the expectation vJer 3:19 b) Zeph 3:7b Ps 31:23*b (opposed to vPs 31:23*a) Ps 66:19; Ps 82:7 (opposed to vPs 82:6) Job 32:8 (opposed to vJob 32:7).

Brown-Driver-Briggs References

Book Refs
Genesis 28:16
Exodus 2:14
1 Samuel 15:32
1 Kings 11:2
Job 32:7 · 32:8
Psalms 31:23* · 66:19 · 82:6 · 82:7
Isaiah 40:7 · 45:15 · 49:4 · 53:3 · 53:4
Jeremiah 3:19 · 3:20 · 3:23 · 4:10 · 8:8
Zephaniah 3:7