Lexical Definition

‎ἀνάθεμα‎ anáthema (an-ath'-em-ah) devoted ^G:N-N
from ‎ἀνατίθεμαι‎

accused, anathema, curse, X great.

• a (religious) ban or (concretely) excommunicated (thing or person)

Abbott-Smith

† ἀνάθεμα, -τος, τό (< ἀνατίθημι), Hellenistic for Attic ἀνάθημα (Bl., § 27, 2);
1. prop. = τὸ ἀνατιθέμένον, that which is laid by to be kept, a votive offering (as ἀνάθημα in II Mac 2:13, Lk 21:5—where LT read -θεμα, v. M, Pr., 46).
2. [As equiv. in LXX for חֵרֶם,] devoted, a thing devoted to God (v. Driver, De., 98 f., and cf. Le 27:28-29), hence;
(a) of the sentence pronounced (De 13:15), a curse: Ac 23:14;
(b) of the object on which the curse is laid, accursed (De 7:26): Ro 9:3, I Co 12:3 16:22, Ga 1:8, 9 (v. ICC on Ro.; Lft., Ga., 1:8, 9; Cremer, 547; Tr., Syn., § v; MM, VGT, s.v.).†

Abbott-Smith References

Liddell-Scott-Jones

ἀνάθεμα,

poetry ἄνθεμα, ατος, τό, (ἀνατίθημι) properly, like{ἀνάθημα}, anything dedicated, [Refs 3rd c.BC+]

__2 anything devoted to evil, an accursed thing, [LXX]; of persons. [NT]
__II curse, [Refs 1st c.AD+]

_{LSJ Scripture Refs: LXX.Lev.27.28 ☩ LXX.Deut.7.26 ☩ Rom.9.3 ☩ 1Cor.12.3}