Lexical Definition

‎πικρῶς‎ pikrōs (pik-roce') bitterly ^G:ADV
adverb from ‎πικρός‎

bitterly.

• bitterly, i.e. (figuratively) violently

Abbott-Smith

πικρῶς, adv. (< πικρός), [in LXX for מַר, מרר pi.;]
bitterly: metaph., (cf. πικρὸν δάκρυον, Hom.), ἔκλαυσε π., Mt 26:75, Lk 22:62 (v. MM, xviii, s.v. παρακολουθέω).†

Abbott-Smith References

Liddell-Scott-Jones

Included with: πικρῶς, ά, όν,

poetry also ός, όν [Refs 8th c.BC+]:—properly pointed, sharp, keen, ὀϊστός [Refs 8th c.BC+]

__II generally, sharp to the sense:
__II.1 of taste, pungent, ῥίζα [Refs 8th c.BC+]; of salt water, opposed to γλυκύς, [Refs 5th c.BC+]; ἁλμυρὸς καὶ π. [Refs 5th c.BC+]; πριγλία π. [Refs 3rd c.BC+]; ἀπ᾽ ὄμφακος πικρᾶς [Refs 4th c.BC+]; ὑγρότης π., opposed to ὀξεῖα, [Refs 4th c.BC+]; also of smell, pungent, [Refs 8th c.BC+]
__II.2 of feeling, sharp, keen, ὠδῖνες [Refs 8th c.BC+]
__II.3 of sound, piercing, shrill, οἰμωγά [Refs]; γόοι, ὄδυρμα, [Refs 5th c.BC+]
__III metaphorically,
__III.1 of things, bitter, especially of what yields pain instead of expected pleasure, frequently in threats, μὴ τάχα πικρὴν Αἴγυπτον καὶ Κύπρον ἵκηαι (variant{ἴδηαι}) [Refs 8th c.BC+]; τιμωρία, ἀγῶνες, [Refs 5th c.BC+]; δύαι, χεῖμα, [Refs 5th c.BC+]: with infinitive, μὴ λίαν πικρὸν εἰπεῖν ᾖ [Refs 4th c.BC+]
__III.2 so of persons, probably in [Refs 7th c.BC+]; γλυκὺν ὧδε φίλοις ἐχθροῖσι δὲ π. [Refs 6th c.BC+]; π. θεοῖς hateful to them, [Refs 5th c.BC+]; ἐμοὶ π. τέθνηκεν ἢ κείνοις γλυκύς his death is matter of sorrow to me, [Refs 5th c.BC+]; δαίμων π., of untimely death (Latin acerbus), [Refs]
__III.3 embittered, angry, πικρὰ ὄρνις [Refs 5th c.BC+]
__III.4 relentless, οὐδὲν πικρότερον τῆς ἀνάγκης [Refs 5th c.BC+]; spiteful, mean, vindictive, βάσκανον καὶ πικρὸν καὶ κακόηθες οὐδέν ἐστι πολίτευμα ἐμόν [Refs 4th c.BC+]: in Comedy texts of old men, σκυθρός, π., φειδωλός [Refs 4th c.BC+] adverb -ρῶς pedantically, [Refs 1st c.BC+]; with rigid accuracy, [Refs 1st c.BC+]
__IV adverb -ρῶς harshly, bitterly, vindictively, [Refs 5th c.BC+]; π. ἔχειν τισί, πρός τινας, [NT+5th c.BC+]: comparative -ότερον[Refs 4th c.BC+]: superlative -ότατα[Refs 8th c.BC+] and Epic dialect; ῐ frequently in Trag., as [Refs 5th c.BC+]: ι therefore is not long by nature as in μικρός.]

_{LSJ Scripture Refs: Matt.26.75}