Lexical Definition

‎ἐπίσημος‎ epísēmos (ep-is'-ay-mos) notable ^G:A
from ‎ἐπί‎ and some form of the base of ‎σημαίνω‎

notable, of note.

• remarkable, i.e. (figuratively) eminent

Abbott-Smith

ἐπίσημος, -ον (< σῆμα, a mark), [in LXX: Ge 30:42 (קָשַׁר), Es 5:4 8:13, I Mac 11:37 14:48, II Mac 15:36, III Mac 6:1 * ;]
1. bearing a mark; of money, stamped, coined.
2. Metaph.,
(a) in good sense, notable, illustrious: Ro 16:7;
(b) in bad sense, notorious: Mt 27:16.†

Abbott-Smith References

Liddell-Scott-Jones

ἐπίσημος-σημος,

Doric dialectἐπίσημος-σᾱμος, ον, (σῆμἀ serving to distinguish, τοῖς δ᾽ ὄνομ᾽ ἄνθρωποι κατέθεντ᾽ ἐ. ἑκάστῳ [Refs 4th c.BC+]

__II. having a mark, inscription or device on it, especially of money, stamped, coined, χρυσὸς ἐ., opposed to ἄσημος, [Refs 5th c.BC+]; so ἀναθήματα οὐκ ἐ. offerings with no inscription on them, [Refs 5th c.BC+]; ἀσπίδες ἐ., opposed to λεῖαι, [Refs 4th c.BC+]
__II.2. of epileptic patients, bearing the marks of the disease, [Refs 5th c.BC+]; of cattle, spotted or striped, [LXX]
__II.3. notable, remarkable, μνῆμ᾽ ἐ. a speaking remembrance, [Refs 5th c.BC+]; εὐνή, λέχος, [Refs]; τάφος ἐπισημότατος [Refs 5th c.BC+]; of garments, fine, [Refs 5th c.BC+]; and of persons, ἐ. σοφίην notable for wisdom, [Refs 5th c.BC+]: in bad sense, conspicuous, notorious, ἐς τὸν ψόγον [Refs 5th c.BC+]; δέσμιος ἐ. [NT+1st c.AD+]
__II.4. significant, οὐκ ἐ. [Refs 2nd c.AD+]
__III. adverb -μως[LXX+2nd c.BC+]: comparative -ότερον[Refs 2nd c.AD+]; -οτέρως [Refs 2nd c.AD+]: superlative -ότατα[Refs 2nd c.AD+]

_{LSJ Scripture Refs: LXX.Gen.30.42 ☩ Matt.27.16 ☩ LXX.Ps.73.4*}